What is the difference between sustained release and extended release wellbutrin

Does anyone else take such I high dose and if so does it give you headaches? Thank youb. I took mg xl and found it gave me massive headaches. I had been on mg for years and felt it had plateaued. I love wellbutrin, lost weight but I just still feel blah. We added Celexa recently but I have a chronic yawn! Hello, my doctor has me taking mg XL twice a day. I have been taking Wellbutrin XL mg and my mood is mostly good. However, I am having a hard time eating.

I just no longer have any energy. I also have a severe sweating problem. This has been going on for years. Does anyone else experience sweating. I have no idea what to expect! I am doing much better on Wellbutrin, but still had some very bad nights. My Dr. I fear he may have forgotten that I was on the SR and not the XL, and just changed the number without really looking it over.

I switched to mail same CVS they sent bupropion 2xday. I almost had a nervous breakdown I was never so scared in my life I thought I was losing my mind horrible. Been on xl for many yrs no problem ne re was so scared in my whole life still dont feel completely right. I was taking bupropion Sr…. I had to stop. I was having dreams that was so vivid that I thought they were real…. I take Wellbutrin XL mg once in the morning, and it has helped my depression, but my anxiety even more so!

But the weird thing is, it was most effective the first day I took it! Why could that be?? Can someone help clarify my dosage from sl to xl please?!? I feel so silly not understanding this.

I have been happily on bupropion sr mg twice daily. My dr unexpectedly switched me to XL I have been teary, down etc but coincided with life stressor. She denied this to be true. Can anyone help me know if mg sr twice daily is equivalent to mg Xl once daily?

Ugh is right. I vote that the pharmacist is correct! Now what are you supposed to do?!? If I understand your question correctly. Read on…. The pharmacist agreed. I agree. Two periods per 24 hour day. Now, you have mg, spread out, spanning a 24 hour period. These curves on the graph tend to overlap. By the way- the curved line on the graph for XL covers approx. Can you call the drug company consumer helpline? Can the pharmacist email or call a rep at the drug company regarding this issue?

Would the doctor do the same? Sometimes a doctor is not a math person, sometimes they listen to their drug rep, who got the math wrong.

Holy cow. Meanwhile, can you get a… 2nd opinion from another doctor? Or from the drug company to the doctor? Please follow up, and if possible let me know what happens next. Hoping for a nice resolution to this. My first few days with Wellbutrin sr were amazing I was very happy I found a way to move forward in life and then after about 6 days it stoped working that way. On the other hand a few weeks after I started the extra insomnia went away.

I noticed that since I started going to the gym has become much harder I used to be addicted to gym. Someone asked why a dr would prescribe sr over xl? By me the concern was making my insomnia worst. Hi i hope soeomo e can help me im on zoloft mg and just stsrted taking wellbutri xl …im not feeling much affect and i feel the worst in yhe am…why id that…i really hope it works for me..

I was on Wellbutrin XL mg, increased some time ago to mg. Do you think it makes sense to switch it to XL twice a day? Checked with my doctor who says its OK but wanted to know if that would be a good idea? Any negative implications? When you and your doctor have determined it is time to stop taking bupropion, the safest way is to taper your dose to reduce the risk of some unpleasant withdrawal symptoms. However, this only needs to take one or two weeks.

Common Wellbutrin or bupropion side effects include but are not limited to:. These side effects will normally resolve over the first one to two weeks as you continue to take the medication. Such symptoms including anxiety , feeling restless, unable to sleep, and shaking may occur if the dosage is increased too quickly.

Conversely, there is some preliminary research and anecdotal evidence that bupropion may help with anxiety in some people. In fact, there are doctors who prescribe Wellbutrin off-label not FDA approved for anxiety disorders.

Wellbutrin may have a side-effect of weight loss. This is the opposite to SSRI antidepressants which can cause weight gain. Studies have shown that if you take Wellbutrin and watch your diet, you can lose significant weight. However, the FDA has not approved Wellbutrin for weight loss.

Bupropion is not suitable for everyone who suffers from depression. You may have a pre-existing medical condition or be taking another medication that would preclude you from being suitable to take bupropion. Many people suffering from depression find such therapies very helpful. Wellbutrin and Lexapro are similar in that they are both antidepressants used to treat major depressive disorder.

The difference is that Wellbutrin also treats seasonal affective disorder SAD while Lexapro is also FDA approved to treat generalized anxiety disorder. Wellbutrin and Lexapro belong to different drug classes. This means that Wellbutrin works in the brain to prevent the reuptake or absorption of dopamine and norepinephrine in addition to preventing the reuptake of serotonin. Both Wellbutrin and Zoloft have some common characteristics.

They are both antidepressants used to treat major depressive disorder. However, Wellbutrin also treats seasonal affective disorder while Zoloft has many other FDA approved uses. These include treating obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder , and premenstrual dysphoric disorder. Wellbutrin and Zoloft belong to different drug classes. As we mentioned above, this means that Wellbutrin works in the brain to prevent the reuptake or absorption of dopamine and norepinephrine in addition to preventing the reuptake of serotonin.

Major depression including seasonal affective disorder can be effectively treated. Once you are being treated, you will feel a noticeable difference in your mood and interest in your daily activities.

If you start to take bupropion, it is very important that you let your family and close friends know you are taking an antidepressant. This is because when you start to take bupropion or other antidepressants, including SSRIs, you are at a greater risk of suicide thoughts or actions. This is especially true in young people aged up to 25 years. These newer antidepressants include norepinephrine and dopamine reuptake inhibitors NDRIs.

Bupropion hydrochloride is a type of NDRI antidepressant. Symptoms ease in spring or early summer. Most people with SAD have depression symptoms every year. SAD is treated with talk therapy, light therapy , and antidepressant medications. In three clinical studies , the XL form of bupropion hydrochloride ER oral tablets was effective for preventing episodes of depression in adults with SAD.

These medications are approved for treating only major depressive disorder and seasonal affective disorder in adults. Short-term clinical studies looked at the SR and XL forms of the drug. Researchers found that children, teenagers, and young adults who took various antidepressants had an increased risk of suicidal actions or thoughts.

This is the most serious warning from the FDA. Other drugs are available that can treat your condition. In fact, many classes of antidepressant drugs can treat major depressive disorder MDD or seasonal affective disorder SAD. Some examples are listed below. Keep in mind that some of the drugs may be a better fit for you than others. Note: Some of the drugs listed here are used off-label to treat these specific conditions. All three drugs are norepinephrine and dopamine reuptake inhibitors NDRIs.

And they have the same active drug: bupropion. SAD also has non-drug treatment options, such as talk therapy or light therapy. With light therapy, you sit by a box that mimics natural sunlight. The bright light may affect brain chemicals that improve mood and sleep, and ease SAD symptoms. These effects include drowsiness, dizziness, headache , and anxiety. In addition, if you have depression , consuming alcohol may worsen your symptoms and affect your mental health.

If you drink alcohol, talk with your doctor before using the SR or XL form of bupropion hydrochloride ER oral tablets. Different interactions can cause different effects.

For instance, some interactions can interfere with how well a drug works. Other interactions can increase the number of side effects or make them more severe. Below is a list of medications that can interact with medications that contain bupropion hydrochloride. This list does not contain all drugs that may interact with these medications.

Before taking either medication, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take.

Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Certain drugs may affect how your body processes bupropion hydrochloride. This may increase your risk for side effects from bupropion hydrochloride or make it less effective at treating your condition. Examples of drugs that may increase your risk for side effects with bupropion hydrochloride include:.

Bupropion hydrochloride may affect how your body processes other drugs. This could increase your risk for side effects from these drugs. Examples of these drugs include:. Other drugs may be less effective when taken with bupropion hydrochloride, such as tamoxifen Soltamox. Because bupropion hydrochloride may cause seizures, it should be used cautiously with drugs that increase your risk for seizures. Bupropion hydrochloride increases the activity of dopamine a type of brain chemical. Side effects may include restlessness, tremor, dizziness, and agitation.

Taking bupropion hydrochloride can increase your blood pressure. These other drugs include:. You should not take bupropion hydrochloride and MOAI drugs within 14 days of each other. In some cases, you may need emergency treatment with linezolid or intravenous IV methylene blue. If you do, your doctor will typically stop your bupropion hydrochloride treatment and monitor you. You should be able to restart your bupropion hydrochloride treatment 24 hours after your last dose of either drug.

No herbs or supplements have been specifically reported to interact with bupropion hydrochloride. However, you should still check with your doctor or pharmacist before using any of these products while taking either medication. No foods have been specifically reported to interact with bupropion hydrochloride. If you have any questions about eating certain foods with this medication, talk with your doctor.

Amphetamines can include illegal drugs and prescription medications used to treat conditions such as attention deficit hyperactivity disorder. This may occur during or after bupropion hydrochloride treatment. Your doctor will order other tests to confirm whether amphetamines are actually in your urine.

To find current prices for either medication in your area, check out GoodRx. The cost you find on GoodRx. Keep in mind that you may be able to get a day supply of the SR or XL form of bupropion hydrochloride ER oral tablets. If approved by your insurance company, getting a day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost.

Before approving coverage for either medication, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered.

Financial assistance may be available to help you pay for the SR or XL form of bupropion hydrochloride ER oral tablets. Medicine Assistance Tool and NeedyMeds are two websites offering resources that may help decrease the price you pay for either medication. The websites also offer tools to help you find low-cost healthcare, as well as educational resources.

To learn more, visit their sites. Some Medicare plans may help cover the cost of mail-order medications. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. Federal Government.

Read our disclaimer for details. Last Update Posted : December 16, Study Description. Detailed Description:. Wellbutrin SR formulation cannot be given as more than mg as a single dose and higher doses are commonly required for the treatment of depression; they also have to be given at least 8 hours apart in order to avoid peak plasma concentrations and to reduce the risk of seizures incidence of 0.

The twice a day dosing may result in complaints of insomnia and may necessitate discontinuing the medication or adding a sleep promoting agent. The benefit of once-daily dosing cannot be understated given treatment adherence is typically lower in depressed patients than their non-depressed counterparts; further, the 8 h dosing interval of bupropion SR is likely to have lower adherence compared with traditional bid dosing i.

The review of Fava et al. Therefore, Wellbutrin XL may improve adherence by eliminating the second dose and Wellbutrin XL also avoids the high plasma drug concentrations at bedtime, as seen with bupropion SR, which are associated with insomnia. Further, the smoother pharmacokinetic profile of Wellbutrin XL may improve overall tolerability compared with Wellbutrin SR. Drug Information available for: Bupropion hydrochloride Bupropion.